Ingredients

COLT'S FOOT - Demulcent (soothing effect), Antitussive (cough suppression)
Leaf extract that has been widely used as a demulcent (soothing effect) and antitussive (cough suppression). It has also been reported to provide symptomatic relief of asthma. Colt's Foot has been evaluated by German Commission E to substantiate efficacy.
Masaki H., Sakaki S. Active Oxygen scavenging activity of plant extracts. Bio Pharm Bull 1995;18:162-166

MANGOSTEEN - Antioxidant, Anti-Inflammatory, Antihistamine
Fruit extract, that contains beneficial xanthones. It can provide antioxidant effect, and can inhibit histamine release. Animal studies have suggested that Mangosteen inhibits cyclooxygenase (COX) and PGE 2 synthesis, thereby suppressing cough.
Nakatani K. Inhibitions of Histamine release and prostaglandin E2 synthesis by mangosteen. Bio Pharm Bull 2002;25:1137-1141

THYME - Antitussive (cough suppression), Antispasmotic (relief of throat closure), Anti-Inflammatory
Leaf extract that contains volatile oils, such as thymol, as well as flavonoids (plant pigments). As a result, thyme commonly is used as an antitussive and antispasmodic. It also contains terpines that stimulate the cilia (fine hairlike structures in the lower respiratory tract) to beat and increase mucous movement to the upper respiratory tract (expectorant action). Furthermore, it has an anti-inflammatory effect, resulting in decreased nitric oxide production. Thyme has been evaluated by German Commission E to substantiate efficacy.
Broucke C. Lemli J. Spasmolytic activity of the flavonoids from Thymus vulgaris. Pharm Weekbl Sci ed 1983;5:9-14

WILD CHERRY BARK - Antitussive (cough suppression), Antioxidant, Mild Sedation
Tree bark extract that contains prunasin, a potent cough suppressant. It has also been reported to have an antioxidant effect. Wild Cherry Bark has, furthermore, been demonstrated to have a mild sedative effect, desirable during periods of illness.
Leung A. Encylopedia of common natural ingredients used in food, drugs and cosmetics, John Wiley & Sons, Inc. New York 1980

QUERCITIN - Antihistamine, Antioxidant
Flavonoid (plant pigment). It both inhibits histamine release, and decreases mast cell reactivity to histamine. It, also, blunts IgE mediated reactions. Quercitin has antioxidant activity by inhibiting cyclooxygenase (COX). It, furthermore, has been shown to decrease PGE2 production, thereby allowing for cough suppression.
Taguchi E. Pharmacological Studies: the anti-inflammatory effect of quercitin. Yakugaku Zasski 1993; 113:327-333

SUNDEW - Antitussive (cough suppression), Antispasmotic (relief of throat closure)
Total plant extract that contains napthaquinones. The napthaquinones not only have an antispasmodic effect, but also have been found to have a profound antitussive effect equal to that of codeine. Sundew has been evaluated by German Commission E to substantiate efficacy.
Schilcher H. Drosera: a proven anti-tussive. Zeitschrift Phytotherapie 1993; 14

BUTTERBUR - Anti-Inflammatory, Demulcent (soothing effect)
Total plant extract that is anti-inflammatory, in that it decreases histamine effect, as well as inhibiting leukotriene formation. It also has been widely used as a demulcent and anti-spasmodic. Butterbur has been evaluated by German Commission E to substantiate efficacy.
Lee D. Butterbur, an herbal remedy confers complementary anti-inflammatory activity in patients receiving corticosteroids. Clin Exp Allergy 2004; 34:110-114

GRAPE SEED EXTRACT with 10% OPC - Antioxidant
Fruit seed extract containing polymers of flavonoids. It exerts remarkable anti-oxidant properties by scavenging free radicals.
Nuttal S. An evaluation of the antioxidant activity of a standardized grape seed extract. J Clin Pharm. Ther 1998;23:385-389